2pwl: Difference between revisions

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==Crystal ~~Strucure~~ of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.==

==Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.==

== Structural highlights ==

<table><tr><td colspan='2'>[[2pwl]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Human Human]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWL OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PWL FirstGlance].

<table><tr><td colspan='2'>[[2pwl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWL OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PWL FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">FGFR2, BEK, KSAM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwl OCA], [http://pdbe.org/2pwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pwl RCSB], [http://www.ebi.ac.uk/pdbsum/2pwl PDBsum]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwl OCA], [http://pdbe.org/2pwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pwl RCSB], [http://www.ebi.ac.uk/pdbsum/2pwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwl ProSAT]</td></tr>

</table>

== Disease ==

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__TOC__

</StructureSection>

~~[[Category: Human]]~~

[[Category: Receptor protein-tyrosine kinase]]

[[Category: Chen, H]]

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-==Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.==
+==Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.==
 <StructureSection load='2pwl' size='340' side='right' caption='[[2pwl]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2pwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PWL FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2pwl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PWL FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2psq|2psq]], [[2pvf|2pvf]], [[2pvy|2pvy]], [[2py3|2py3]], [[2pz5|2pz5]], [[2pzp|2pzp]], [[2pzr|2pzr]], [[2q0b|2q0b]]</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FGFR2, BEK, KSAM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwl OCA], [http://pdbe.org/2pwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pwl RCSB], [http://www.ebi.ac.uk/pdbsum/2pwl PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwl OCA], [http://pdbe.org/2pwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pwl RCSB], [http://www.ebi.ac.uk/pdbsum/2pwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwl ProSAT]</span></td></tr>
 </table>
 == Disease ==
@@ Line 39: / Line 39: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
 [[Category: Receptor protein-tyrosine kinase]]
 [[Category: Chen, H]]