1ftd: Difference between revisions

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[[Image:1ftd.gif|left|200px]]
[[Image:1ftd.gif|left|200px]]


{{Structure
<!--
|PDB= 1ftd |SIZE=350|CAPTION= <scene name='initialview01'>1ftd</scene>, resolution 2.&Aring;
The line below this paragraph, containing "STRUCTURE_1ftd", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=E97:[3-(4-{2&#39;-[4-(3-DIMETHYLAMINO-PROPOXY)-PHENYL]-3H,3&#39;H-[5,5&#39;]BIBENZOIMIDAZOLYL-2-YL}-PHENOXY)-PROPYL]-DIMETHYL-AMINE'>E97</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1ftd| PDB=1ftd  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ftd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ftd OCA], [http://www.ebi.ac.uk/pdbsum/1ftd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ftd RCSB]</span>
}}


'''5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'-SYMMETRIC BIS-BENZIMIDAZOLE COMPLEX'''
'''5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'-SYMMETRIC BIS-BENZIMIDAZOLE COMPLEX'''
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==About this Structure==
==About this Structure==
1FTD is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FTD OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FTD OCA].  


==Reference==
==Reference==
A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity., Mann J, Baron A, Opoku-Boahen Y, Johansson E, Parkinson G, Kelland LR, Neidle S, J Med Chem. 2001 Jan 18;44(2):138-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11170623 11170623]
A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity., Mann J, Baron A, Opoku-Boahen Y, Johansson E, Parkinson G, Kelland LR, Neidle S, J Med Chem. 2001 Jan 18;44(2):138-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11170623 11170623]
[[Category: Protein complex]]
[[Category: Baron, A.]]
[[Category: Baron, A.]]
[[Category: Johansson, E.]]
[[Category: Johansson, E.]]
Line 31: Line 27:
[[Category: Opoku-Boahen, Y.]]
[[Category: Opoku-Boahen, Y.]]
[[Category: Parkinson, G.]]
[[Category: Parkinson, G.]]
[[Category: minor groove binding]]
[[Category: Minor groove binding]]
 
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