1ftn: Difference between revisions

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[[Image:1ftn.jpg|left|200px]]
[[Image:1ftn.jpg|left|200px]]


{{Structure
<!--
|PDB= 1ftn |SIZE=350|CAPTION= <scene name='initialview01'>1ftn</scene>, resolution 2.1&Aring;
The line below this paragraph, containing "STRUCTURE_1ftn", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=GDP:GUANOSINE-5&#39;-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE= SYNTHETIC HUMAN RHOA GENE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_1ftn| PDB=1ftn  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ftn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ftn OCA], [http://www.ebi.ac.uk/pdbsum/1ftn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ftn RCSB]</span>
}}


'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''
'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''
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[[Category: Wei, Y.]]
[[Category: Wei, Y.]]
[[Category: Zhang, Y.]]
[[Category: Zhang, Y.]]
[[Category: gtp-binding]]
[[Category: Gtp-binding]]
[[Category: lipoprotein]]
[[Category: Lipoprotein]]
[[Category: prenylation]]
[[Category: Prenylation]]
[[Category: proto-oncogene]]
[[Category: Proto-oncogene]]
[[Category: small p-protein]]
[[Category: Small p-protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 16:45:09 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:30:08 2008''

Revision as of 13:45, 2 May 2008

File:1ftn.jpg

Template:STRUCTURE 1ftn

CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX


Overview

RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.

About this Structure

1FTN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995 Page seeded by OCA on Fri May 2 16:45:09 2008

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