1ftn: Difference between revisions
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'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX''' | '''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX''' | ||
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[[Category: Wei, Y.]] | [[Category: Wei, Y.]] | ||
[[Category: Zhang, Y.]] | [[Category: Zhang, Y.]] | ||
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[[Category: | [[Category: Prenylation]] | ||
[[Category: | [[Category: Proto-oncogene]] | ||
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Revision as of 13:45, 2 May 2008
CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Overview
RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.
About this Structure
1FTN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995 Page seeded by OCA on Fri May 2 16:45:09 2008