Journal:Protein Science:2: Difference between revisions
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<scene name='72/725874/Cv1/17'>Interactions of MB and DECA with the indole moiety of Trp84 in their complexes with TcAChE in crystals obtained using AS as the precipitant</scene>. The <span style="color:lime;background-color:black;font-weight:bold;">indole of Trp84 is displayed in space-filling mode, with carbon atoms colored green</span>. MB and DECA are depicted as ball-and-sticks models, with their carbon atoms in <span style="color:cyan;background-color:black;font-weight:bold;">cyann</span> and <font color='magenta'><b>magenta</b></font>, respectively. Whereas the proximal quaternary group of MB interacts with the five-membered ring of the indole, the DECA extends further, such that its proximal quaternary group interacts with the indole’s six-membered ring. | <scene name='72/725874/Cv1/17'>Interactions of MB and DECA with the indole moiety of Trp84 in their complexes with TcAChE in crystals obtained using AS as the precipitant</scene>. The <span style="color:lime;background-color:black;font-weight:bold;">indole of Trp84 is displayed in space-filling mode, with carbon atoms colored green</span>. MB and DECA are depicted as ball-and-sticks models, with their carbon atoms in <span style="color:cyan;background-color:black;font-weight:bold;">cyann</span> and <font color='magenta'><b>magenta</b></font>, respectively. Whereas the proximal quaternary group of MB interacts with the five-membered ring of the indole, the DECA extends further, such that its proximal quaternary group interacts with the indole’s six-membered ring. | ||
Docking of MB into the X-ray structure obtained using crystals grown from PEG200, ''viz.'', MB-PEG/TcAChE, yields a <scene name='72/725874/Cv2/2'>pose that closely resembles the position of the ligand in the crystal structure</scene>. | |||
*<scene name='72/725874/Bug/1'>Bug1</scene>. | *<scene name='72/725874/Bug/1'>Bug1</scene>. | ||
This page complements a publication in scientific journals and is one of the Proteopedia's Interactive 3D Complement pages. For additional details please see I3DC.
