Atropine: Difference between revisions
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The proper dose of atropine is approximately 0.1 mg/ml in adults and 0.05 mg/ml in children when taken orally or given intravenously <ref>Atropine. http://www.rxlist.com/atropine-drug.htm </ref>. Atropine can be given orally, intravenously, rectally, or topically, and in veterinary medicine, it can be given intramuscularly or subcutaneously. | The proper dose of atropine is approximately 0.1 mg/ml in adults and 0.05 mg/ml in children when taken orally or given intravenously <ref>Atropine. http://www.rxlist.com/atropine-drug.htm </ref>. Atropine can be given orally, intravenously, rectally, or topically, and in veterinary medicine, it can be given intramuscularly or subcutaneously. | ||
== '''Interaction of Atropine with Phospholipase | == '''Interaction of Atropine with Phospholipase A2''' == | ||
<scene name='42/420811/Cv/1'>Atropine in complex with phospholipase A2</scene> ([[1th6]]). | <scene name='42/420811/Cv/1'>Atropine in complex with phospholipase A2</scene> ([[1th6]]). | ||
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The image to the above shows the membrane-bound phospholipase A2 in blue <ref> pla2. http://www.ks.uiuc.edu/Research/smd_imd/pla2/pla2.gif </ref>. | The image to the above shows the membrane-bound phospholipase A2 in blue <ref> pla2. http://www.ks.uiuc.edu/Research/smd_imd/pla2/pla2.gif </ref>. | ||
==== '''Atropine in the Active Site of Phospholipase | ==== '''Atropine in the Active Site of Phospholipase A2''' ==== | ||
Atropine is an inhibitor of phospholipase 2A, and can be seen in complex with this enzyme on the left. The <scene name='Sandbox_53/Atropine_structure/1'>structure of atropine</scene> can be seen more clearly in gray using the ball-and stick representation of the drug and protein. It can also be seen in green in this <scene name='Sandbox_53/Phospholipase2a_composition/1'>space-filling model</scene>, where protein appears in brown, ligands appear in green, and solvents appear in blue. Finally, the | Atropine is an inhibitor of phospholipase 2A, and can be seen in complex with this enzyme on the left. The <scene name='Sandbox_53/Atropine_structure/1'>structure of atropine</scene> can be seen more clearly in gray using the ball-and stick representation of the drug and protein. It can also be seen in green in this <scene name='Sandbox_53/Phospholipase2a_composition/1'>space-filling model</scene>, where protein appears in brown, ligands appear in green, and solvents appear in blue. Finally, the | ||
