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| | | REMOVED: The PDB entry 5ic2 was removed. |
| ==Product-Complex of E.coli 5-Amino Laevulinic Acid Dehydratase==
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| <StructureSection load='5ic2' size='340' side='right' caption='[[5ic2]], [[Resolution|resolution]] 2.10Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[5ic2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IC2 FirstGlance]. <br>
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| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PBG:3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>PBG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b4e|1b4e]]</td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Porphobilinogen_synthase Porphobilinogen synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.24 4.2.1.24] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ic2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ic2 OCA], [http://pdbe.org/5ic2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ic2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ic2 PDBsum]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/HEM2_ECOLI HEM2_ECOLI]] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
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| __TOC__
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| </StructureSection>
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| [[Category: Porphobilinogen synthase]]
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| [[Category: Cooper, J B]]
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| [[Category: Erskine, P T]]
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| [[Category: Norton, E]]
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| [[Category: Shoolingin-Jordan, P M]]
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| [[Category: Dehydratase]]
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| [[Category: Lyase]]
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| [[Category: Tetrapyrrole biosynthesis]]
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