Sandbox Reserved 433: Difference between revisions
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[[Student Projects for UMass Chemistry 423 Spring 2016]] | [[Student Projects for UMass Chemistry 423 Spring 2016]] | ||
<StructureSection load='2yly' size='350' side='right' caption=' | <StructureSection load='2yly' size='350' side='right' caption='p-hydroxybenzenesulphonamides ERb receptor (PDB entry [[2yly]])' scene=''> | ||
==Introduction== | ==Introduction== | ||
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- The sulphonamide oxygens pack against Met336 and the benzyl group at top of the pocket comes near His475 but does not form any coulombic interactions but Van der Waals interactions exist near the pocket. | - The sulphonamide oxygens pack against Met336 and the benzyl group at top of the pocket comes near His475 but does not form any coulombic interactions but Van der Waals interactions exist near the pocket. | ||
- Complexes make H-bonding interactions not only with Arg346 and Glu305 but also His475 | - Complexes make H-bonding interactions not only with Arg346 (yellow) and Glu305 (blue) but also His475 (green). Binding sites are shown <scene name='48/483890/2yly_binding2/1'>here</scene> | ||
