5ieg: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5ieg is ~~ON HOLD until Paper Publication~~

==Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin==

~~Authors~~: ~~Caputo~~, A.T., ~~Roversi~~, P., ~~Alonzi~~, D.S., ~~Kiappes, J~~.L., ~~Zitzmann, N~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5ieg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IEG OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IEG FirstGlance].

~~Description~~: ~~Murine endoplasmic reticulum~~ alpha-glucosidase II ~~with N-9'-methoxynonyl-1-deoxynojirimycin~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=6A9:N-9-METHOXYNONYL-1-DEOXYNOJIRIMYCIN'>6A9</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.84 3.2.1.84] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ieg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ieg OCA], [http://pdbe.org/5ieg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ieg RCSB], [http://www.ebi.ac.uk/pdbsum/5ieg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ieg ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GANAB_MOUSE GANAB_MOUSE]] Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. [[http://www.uniprot.org/uniprot/GLU2B_MOUSE GLU2B_MOUSE]] Regulatory subunit of glucosidase II.<ref>PMID:9148925</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Hydrolase]]

[[Category: Alonzi, D S]]

[[Category: Caputo, A T]]

[[Category: Kiappes, J L]]

[[Category: Roversi, P]]

[[Category: Zitzmann, N]]

[[Category: ~~Alonzi, D.S~~]]

[[Category: Enzyme glycosyl hydrolase gh31 quality control exoglycosidase]]

[[Category: ~~Kiappes, J.L]]~~

[[Category: Mon-dnj]]

~~[[Category: Caputo, A.T]]~~

~~[[Category: Roversi, P~~]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5ieg is ON HOLD  until Paper Publication
+==Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin==
+<StructureSection load='5ieg' size='340' side='right' caption='[[5ieg]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
-Authors: Caputo, A.T., Roversi, P., Alonzi, D.S., Kiappes, J.L., Zitzmann, N.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ieg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IEG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IEG FirstGlance]. <br>
-Description: Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6A9:N-9-METHOXYNONYL-1-DEOXYNOJIRIMYCIN'>6A9</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f0e|5f0e]], [[5hjo|5hjo]], [[5hjr|5hjr]], [[5h9o|5h9o]], [[5ied|5ied]], [[5iee|5iee]], [[5ief|5ief]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.84 3.2.1.84] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ieg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ieg OCA], [http://pdbe.org/5ieg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ieg RCSB], [http://www.ebi.ac.uk/pdbsum/5ieg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ieg ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GANAB_MOUSE GANAB_MOUSE]] Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. [[http://www.uniprot.org/uniprot/GLU2B_MOUSE GLU2B_MOUSE]] Regulatory subunit of glucosidase II.<ref>PMID:9148925</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Hydrolase]]
+[[Category: Alonzi, D S]]
+[[Category: Caputo, A T]]
+[[Category: Kiappes, J L]]
+[[Category: Roversi, P]]
 [[Category: Zitzmann, N]]
-[[Category: Alonzi, D.S]]
+[[Category: Enzyme glycosyl hydrolase gh31 quality control exoglycosidase]]
-[[Category: Kiappes, J.L]]
+[[Category: Mon-dnj]]
-[[Category: Caputo, A.T]]
-[[Category: Roversi, P]]