5ii0: Difference between revisions
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==Crystal structure of the human calcitonin receptor ectodomain in complex with a truncated salmon calcitonin analogue== | |||
<StructureSection load='5ii0' size='340' side='right' caption='[[5ii0]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ii0]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5II0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5II0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr> | |||
[[ | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4BF:4-BROMO-L-PHENYLALANINE'>4BF</scene>, <scene name='pdbligand=LPD:L-PROLINAMIDE'>LPD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ii0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ii0 OCA], [http://pdbe.org/5ii0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ii0 RCSB], [http://www.ebi.ac.uk/pdbsum/5ii0 PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CALCR_HUMAN CALCR_HUMAN]] This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Johansson, E]] | [[Category: Johansson, E]] | ||
[[Category: Reedtz-Runge, S]] | [[Category: Reedtz-Runge, S]] | ||
[[Category: Calcitonin]] | |||
[[Category: Ectodomain]] | |||
[[Category: G protein coupled receptor]] | |||
[[Category: Hormone]] | |||
[[Category: Peptide hormone]] | |||
Revision as of 17:12, 15 May 2016
Crystal structure of the human calcitonin receptor ectodomain in complex with a truncated salmon calcitonin analogue
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