1gth: Difference between revisions

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[[Image:1gth.gif|left|200px]]
[[Image:1gth.gif|left|200px]]


{{Structure
<!--
|PDB= 1gth |SIZE=350|CAPTION= <scene name='initialview01'>1gth</scene>, resolution 2.25&Aring;
The line below this paragraph, containing "STRUCTURE_1gth", creates the "Structure Box" on the page.
|SITE= <scene name='pdbsite=FA1:Ura+Binding+Site+For+Chain+D'>FA1</scene>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=IDH:(5S)-5-IODODIHYDRO-2,4(1H,3H)-PYRIMIDINEDIONE'>IDH</scene>, <scene name='pdbligand=IUR:5-IODOURACIL'>IUR</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidine_dehydrogenase_(NADP(+)) Dihydropyrimidine dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.2 1.3.1.2] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1gth| PDB=1gth  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gth OCA], [http://www.ebi.ac.uk/pdbsum/1gth PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1gth RCSB]</span>
}}


'''DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL'''
'''DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL'''
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==Reference==
==Reference==
Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer., Dobritzsch D, Ricagno S, Schneider G, Schnackerz KD, Lindqvist Y, J Biol Chem. 2002 Apr 12;277(15):13155-66. Epub 2002 Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11796730 11796730]
Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer., Dobritzsch D, Ricagno S, Schneider G, Schnackerz KD, Lindqvist Y, J Biol Chem. 2002 Apr 12;277(15):13155-66. Epub 2002 Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11796730 11796730]
[[Category: Dihydropyrimidine dehydrogenase (NADP(+))]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Schneider, G.]]
[[Category: Schneider, G.]]
[[Category: 5-fluorouracil degradation]]
[[Category: 5-fluorouracil degradation]]
[[Category: electron transfer]]
[[Category: Electron transfer]]
[[Category: flavin]]
[[Category: Flavin]]
[[Category: iron-sulfur cluster]]
[[Category: Iron-sulfur cluster]]
[[Category: oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: pyrimidine catabolism]]
[[Category: Pyrimidine catabolism]]
 
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