GTP-binding protein: Difference between revisions

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[[Image:2nzj.png|left|200px|thumb|Crystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide [[2nzj]]]]
[[Image:2nzj.png|left|200px|thumb|Crystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide [[2nzj]]]]
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== Function ==
== Function ==
'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell.  They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: '''heterotrimeric G proteins'''<ref>PMID:14762218</ref> and '''small GTPases'''<ref>PMID:11152757</ref>.  The structure of small GTPase is homologous to that of the α subunit of heterotrimeric G protein.  See details on GTP-binding protein LepA in [[LepA]].
'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell.  They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: '''heterotrimeric G proteins'''<ref>PMID:14762218</ref> and '''small GTPases'''<ref>PMID:11152757</ref>.  The structure of small GTPase is homologous to that of the α subunit of heterotrimeric G protein.  See details on GTP-binding protein LepA in [[LepA]].