Sandbox Reserved 1168: Difference between revisions
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Neurotensin== | |||
<scene name='72/721539/Nts8_13/1'>Neurotensin(NTS)</scene> is a 13-amino acid peptide originally isolated from bovine hypothalamus. It fulfills the role of both a neurotransmitter and a neuromodulator in the nervous system and a hormone in the periphery. NTS is a neuromodulator of dopamine transmission and of anterior pituitary hormone secretion. It is also a paracrine and endocrine modulator in the periphery of the digestive tract and cardiovascular system. Finally, NTS serves as a growth factor for many normal and cancerous cell types.(Vincent) | |||
Only the C-terminal tail of NTS, amino acids 8-13, were resolved in the crystal structure. | |||
== Function == | == Function == | ||
<scene name='72/721539/Binding_site_charges/2'>Binding Site Charges</scene> | <scene name='72/721539/Binding_site_charges/2'>Binding Site Charges</scene> | ||
<scene name='72/721539/Binding_pocket_surface/2'>Binding Site Surface</scene> | <scene name='72/721539/Binding_pocket_surface/2'>Binding Site Surface</scene> | ||
