Sandbox Reserved 1177: Difference between revisions

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===Na+ Binding Pocket===
===Na+ Binding Pocket===


W321, which is positioned at the bottom of the hydrophobic pocket(green link from allie), sets the top of the Na+ ion binding pocket. The Na+ ion binding pocket acts as a negative allosteric site for G protein activity. When Na+ enters the Na+ ion binding pocket, it interacts with Asp 113, and shuts down the activity of the protein. When the G protein is in its active state, the Na+ ion binding pocket is collapsed, preventing the entrance of Na+.  
W321, which is positioned at the bottom of the hydrophobic pocket(green link from allie), sets the top of the <scene name='72/721548/Na_bind_pocket/12'>Na+ Binding Pocket</scene>. The Na+ ion binding pocket acts as a negative allosteric site for G protein activity. When Na+ enters the Na+ ion binding pocket, it interacts with Asp 113, and shuts down the activity of the protein. When the G protein is in its active state, the Na+ ion binding pocket is collapsed, preventing the entrance of Na+.  
   
   
<scene name='72/721548/Na_bind_pocket/12'>Na+ Binding Pocket</scene>
 
== Function ==
== Function ==



Revision as of 19:13, 25 March 2016

Figure Legend

NTSR1-ELF, Rattus norvegicus

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References