Sandbox Reserved 1168: Difference between revisions
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== Binding Site == | == Binding Site == | ||
Binding of NTS to the binding site is enriched by <scene name='72/721539/Binding_pocket_surface/2'>charge complementarity</scene> between the positive NTS arginine side chains and the electronegative pocket. In addition, the C-terminus forms a <scene name='72/721539/Binding_site_charges/2'>salt bridge</scene> with | Binding of NTS to the binding site is enriched by <scene name='72/721539/Binding_pocket_surface/2'>charge complementarity</scene> between the positive NTS arginine side chains and the electronegative pocket. In addition, the C-terminus forms a <scene name='72/721539/Binding_site_charges/2'>salt bridge</scene> with R328. Only three out of eight hydrogen bonds are made between the side chains of NTS and the receptor. Most of the interactions are van der Waals interactions. The binding pocket is partially capped by a hairpin loop at the proximal end of the receptor protein's N-terminus. (White) | ||
== Function == | == Function == | ||
