Sandbox Reserved 1174: Difference between revisions
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=== Structural Stabilization === | === Structural Stabilization === | ||
There are many different stabilizing factors in the structure of this receptor. There are three native disulfide bonds in the extracellular region. One of these bonds constrains the N terminal helix to extracellular loop 2. The <scene name='72/721545/N-terminus/1'>N-terminus</scene> functions like a cap on the extracellular side of the protein, packing tightly against ECL1 and ECL2. It also provides <scene name='72/721545/34_39_40/2'>polar amino acids</scene> that interact with the ligand when bound. | There are many different stabilizing factors in the structure of this receptor. There are three native <scene name='72/721545/Disulfides/1'>disulfide bonds</scene> in the extracellular region. One of these bonds constrains the N terminal helix to extracellular loop 2. The <scene name='72/721545/N-terminus/1'>N-terminus</scene> functions like a cap on the extracellular side of the protein, packing tightly against ECL1 and ECL2. It also provides <scene name='72/721545/34_39_40/2'>polar amino acids</scene> that interact with the ligand when bound. | ||
=== Binding Pocket === | === Binding Pocket === | ||
