Sandbox Reserved 1167: Difference between revisions
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The Class B GPCR has the longest and deepest binding pocket. The distance between the EC tips of Helicies II and VI as well as between the tips between Helicies III and VII are some of the largest among the GPCRs. | The Class B GPCR has the longest and deepest binding pocket. The distance between the EC tips of Helicies II and VI as well as between the tips between Helicies III and VII are some of the largest among the GPCRs. | ||
=== Unique | ====Other Unique Structural Features ==== | ||
An important interface stabilization interaction between helices I and VII occurs between [https://en.wikipedia.org/wiki/Serine Ser] 152 of Helix I and Ser 390 of Helix VII. Due to their close proximity to one another, they form an important <scene name='72/721537/Ser-ser_hydrogen_bond/2'>hydrogen bond</scene> which serves to stabilize the structure of GCGR. | An important interface stabilization interaction between helices I and VII occurs between [https://en.wikipedia.org/wiki/Serine Ser] 152 of Helix I and Ser 390 of Helix VII. Due to their close proximity to one another, they form an important <scene name='72/721537/Ser-ser_hydrogen_bond/2'>hydrogen bond</scene> which serves to stabilize the structure of GCGR. | ||