Sandbox Reserved 1167: Difference between revisions

Revision as of 02:47, 30 March 2016 view source Alexis Coulis (talk \| contribs) 137 edits No edit summary ← Older edit		Revision as of 02:59, 30 March 2016 view source Alexis Coulis (talk \| contribs) 137 edits No edit summary Newer edit →
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	== Function ==		== Function ==

	The Glucagon Receptor plays an important role in glucose homeostasis. During times of fasting (or low blood sugar) the pancreas dispatches glucagon to activate the GCGR in the liver. The [http://www.nature.com/nature/journal/v499/n7459/fig_tab/nature12393_F5.html binding of glucagon] ~~with its receptor~~ stimulates gluconeogenesis, through ~~adenyllate~~ cyclase that initiates protein kinase A (PKA) activity<ref>PMID:PMC4321206</ref>. This pathway synthesizes glucose, elevating blood sugar levels.		The Glucagon Receptor plays an important role in glucose homeostasis. During times of fasting (or low blood sugar) the pancreas dispatches glucagon to activate the GCGR in the liver. The [http://www.nature.com/nature/journal/v499/n7459/fig_tab/nature12393_F5.html binding of glucagon] stimulates gluconeogenesis, through adenylate cyclase that initiates protein kinase A (PKA) activity<ref>PMID:PMC4321206</ref>. This pathway synthesizes glucose, elevating blood sugar levels.

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