Sandbox Reserved 1174: Difference between revisions
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=== Cancer === | === Cancer === | ||
Many of the functions of LPA<sub>1</sub>, i.e. cell proliferation, survival, and morphology, are implicated in cancers. | Many of the functions of LPA<sub>1</sub>, i.e. cell proliferation, survival, and morphology, are implicated in cancers. LPA has been shown to support metastasis (spreading) of breast and ovarian cancer to the bones. Inhibition of LPA<sub>1</sub> has been shown to significantly reduce this progression, and therefore may be a promising treatment for patients with bone metastasis. <ref name= "Boucharaba" DOI: 10.1073/pnas.0600979103 </ref> | ||
===Pain=== | ===Pain=== | ||
