Sandbox Reserved 1174: Difference between revisions
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=== Binding Pocket === | === Binding Pocket === | ||
The <scene name='72/721545/Ligand/1'>binding pocket</scene> for LPA inside the receptor consists of both polar and nonpolar residues. There are <scene name='72/721545/All_polar_interactions/4'>polar</scene> residues on the N terminus and within the binding pocket (<scene name='72/721545/All_polar_interactions/3'>polar residues</scene>). There is also a <scene name='72/721545/Hydrophobic_pocket/2'>hydrophobic pocket</scene> that interacts with the long acyl chain of LPA. | The ligand shown in this structure is ONO-9780307. It similar in structure to LPA, and was bound to LPA<sub>1</sub> for crystallization to visualize the binding pocket. <ref name= "Moolenar" </ref> The <scene name='72/721545/Ligand/1'>binding pocket</scene> for LPA inside the receptor consists of both polar and nonpolar residues. There are <scene name='72/721545/All_polar_interactions/4'>polar</scene> residues on the N terminus and within the binding pocket (<scene name='72/721545/All_polar_interactions/3'>polar residues</scene>). There is also a <scene name='72/721545/Hydrophobic_pocket/2'>hydrophobic pocket</scene> that interacts with the long acyl chain of LPA. | ||
=== Sphingosine-1-Phosphate Receptor === | === Sphingosine-1-Phosphate Receptor === | ||
