Homocitrate synthase: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
The HS <scene name='46/465446/Cv/6'>active site is located in the interior of the N-terminal TIM-barrel domain</scene>. <scene name='46/465446/Cv/3'>Whole active site</scene>. The <scene name='46/465446/Cv/5'>metal ion is octahedrally coordinated to the protein and to the 2-oxoglutarate</scene><ref>PMID:19776021</ref>. Water molecules shown as red spheres.  
The HS <scene name='46/465446/Cv/7'>active site is located in the interior of the N-terminal TIM-barrel domain</scene>. <scene name='46/465446/Cv/8'>Active site</scene>. The <scene name='46/465446/Cv/9'>metal ion is octahedrally coordinated to the protein and to the 2-oxoglutarate</scene><ref>PMID:19776021</ref>. Water molecules shown as red spheres.  
</StructureSection>
</StructureSection>
== 3D Structures of homocitrate synthase ==
== 3D Structures of homocitrate synthase ==

Revision as of 12:54, 16 May 2019

Fission yeast homocitrate synthase Lys4 dimer complex with 2-oxoglutarate, Na+ (purple) and Zn+2 (grey) ions 3ivt

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3D Structures of homocitrate synthase

Updated on 16-May-2019

3ivs – fyHS Lys4 – fission yeast
3ivt, 3ivu - fyHS Lys4 + 2-oxoglutarate
3mi3 - fyHS Lys4 + lysine
2ztj – TtHS + α-ketoglutarate – Thermus thermophilus
2zyf - TtHS + α-ketoglutarate + Mg
2ztk – TtHS + homocitrate
3a9i – TtHS + lysine

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky