Sandbox Reserved 1160: Difference between revisions
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=== Binding Pocket === | === Binding Pocket === | ||
[[Image: Organic with clipped surface.png|200 px|left|thumb|Cross section view of mavoglurant in the binding pocket]] | [[Image: Organic with clipped surface.png|200 px|left|thumb|Cross section view of mavoglurant in the binding pocket]] | ||
The binding pocket represents an interesting source of regulatory control. The binding pocket is only accessible by a relatively narrow (7 angstrom) <scene name='72/721531/Protien_sur/4'>entrance</scene><ref name="Dore" />. This small entrance severely restricts the access of both positive and negative allosteric regulators. | The binding pocket represents an interesting source of regulatory control. The binding pocket is only accessible by a relatively narrow (7 angstrom) <scene name='72/721531/Protien_sur/4'>entrance</scene><ref name="Dore" />. This small entrance severely restricts the access of both positive and negative allosteric regulators. | ||
One such regulator, mavoglurant, is a | |||
Important Amino Acids<ref name="Dore" />: | Important Amino Acids<ref name="Dore" />: | ||
