Sandbox Reserved 427: Difference between revisions

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==Introduction==

~~Vitamin D binding protein Overview:~~

Vitamin D-binding protein belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and other cell types as a surface protein. It is synthesized in the liver and is prevalent throughout the body. DBP is a major carrier of vitamin D3 and all of its metabolites. The active D3 hormone is critical for the maintenance of calcium levels, bone health, and regulates cell proliferation. This makes the D3 hormone of a compound of interest for many therapies, and by conjunction gives importance to DBP which can affect the pharmacokinetics of the D3 hormone. DBP ensures continuous metabolism of D3 hormone derived from human skin cells, and functions as storage for the hormone. Being part of the Human Serum Albumin family, it has similar structural components, however the unique interactions of DBP can be attributed to the arrangement of the helices of <scene name='48/483884/Domain_i/3'>Domain I</scene>, shown in color. Since vitamin D3 analogs have so much potential as therapies, the understanding of DBP’s structure and binding properties could yield brand new in-sites into the workings of vitamin D3 pathways. This would allow the creation of new, more specific therapies centered around vitamin D3 metabolism.

Vitamin D-binding protein belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and other cell types as a surface protein. DBP is a major carrier of vitamin D3 and all of its metabolites. The active D3 hormone is critical for the maintenance of calcium levels, bone health, and regulates cell proliferation. This makes the D3 hormone of a compound of interest for many therapies, and by conjunction gives importance to DBP which can affect the pharmacokinetics of the D3 hormone. DBP ensures continuous metabolism of D3 hormone derived from human skin cells, and functions as storage for the hormone. Being part of the Human Serum Albumin family, it has similar structural components, however the unique interactions of DBP can be attributed to the arrangement of the helices of <scene name='48/483884/Domain_i/3'>Domain I</scene>, shown in color. Since vitamin D3 analogs have so much potential as therapies, the understanding of DBP’s structure and binding properties could yield brand new in-sites into the workings of vitamin D3 pathways. This would allow the creation of new, more specific therapies centered around vitamin D3 metabolism.

Sandbox Reserved 427: Difference between revisions

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@@ Line 12: / Line 12: @@
 ==Introduction==
-Vitamin D binding protein Overview:
+Vitamin D-binding protein belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and other cell types as a surface protein. It is synthesized in the liver and is prevalent throughout the body. DBP is a major carrier of vitamin D3 and all of its metabolites. The active D3 hormone is critical for the maintenance of calcium levels, bone health, and regulates cell proliferation. This makes the D3 hormone of a compound of interest for many therapies, and by conjunction gives importance to DBP which can affect the pharmacokinetics of the D3 hormone. DBP ensures continuous metabolism of D3 hormone derived from human skin cells, and functions as storage for the hormone. Being part of the Human Serum Albumin family, it has similar structural components, however the unique interactions of DBP can be attributed to the arrangement of the helices of <scene name='48/483884/Domain_i/3'>Domain I</scene>, shown in color. Since vitamin D3 analogs have so much potential as therapies, the understanding of DBP’s structure and binding properties could yield brand new in-sites into the workings of vitamin D3 pathways. This would allow the creation of new, more specific therapies centered around vitamin D3 metabolism.
-Vitamin D-binding protein belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and other cell types as a surface protein.  DBP is a major carrier of vitamin D3 and all of its metabolites. The active D3 hormone is critical for the maintenance of calcium levels, bone health, and regulates cell proliferation. This makes the D3 hormone of a compound of interest for many therapies, and by conjunction gives importance to DBP which can affect the pharmacokinetics of the D3 hormone. DBP ensures continuous metabolism of D3 hormone derived from human skin cells, and functions as storage for the hormone. Being part of the Human Serum Albumin family, it has similar structural components, however the unique interactions of DBP can be attributed to the arrangement of the helices of <scene name='48/483884/Domain_i/3'>Domain I</scene>, shown in color. Since vitamin D3 analogs have so much potential as therapies, the understanding of DBP’s structure and binding properties could yield brand new in-sites into the workings of vitamin D3 pathways. This would allow the creation of new, more specific therapies centered around vitamin D3 metabolism.