Sandbox Reserved 1167: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 34: Line 34:
==== Binding Pocket ====
==== Binding Pocket ====


The class B GPCR has the widest and longest binding pocket. The distance between the EC tips of Helicies II and VI  as well as between the tips of Helicies III and VII are some of the largest among the GPCRs<ref>PMID:23863937</ref>. As a result, the [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820480/bin/nihms495648f2.jpg binding cavity] of GCGR is located deeper inside the molecule.  
The class B GPCR has the widest and longest binding pocket. The distance between the EC tips of Helicies II and VI  as well as between the tips of Helicies III and VII are some of the largest among the GPCRs<ref name="structure_article" />. As a result, the [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820480/bin/nihms495648f2.jpg binding cavity] of GCGR is located deeper inside the molecule.  


====Other Unique Structural Features ====
====Other Unique Structural Features ====