Sandbox WWC3: Difference between revisions
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==Structure== | ==Structure== | ||
As noted above, the sodium channel consists of an alpha and two beta subunits. However, the alpha subunit is the only part necessary for the function of the channel <ref name = "sod/>. The alpha subunit, depicted right, consists of four repeating structures, named I through IV <ref name ="struct"> DOI: 10.1111/j.1469-7793.1998.647bp.x </ref>. | As noted above, the sodium channel consists of an alpha and two beta subunits. However, the alpha subunit is the only part necessary for the function of the channel <ref name = "sod"/>. The alpha subunit, depicted right, consists of four repeating structures, named I through IV <ref name ="struct"> DOI: 10.1111/j.1469-7793.1998.647bp.x </ref>. These structures consist of six transmembrane alpha helices named S1 through S6 <ref name = "struct"/>. Interestingly, each repeating subunit resembles a bacterial K+ channel <ref name = "struct"/>. These subunits fold together to form a central pore, and this complete structure resembles a bacterial Ca2+ channel <ref name = "struct"/>. | ||
