Sandbox WWC2: Difference between revisions

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==Introduction==

''Monoamine oxidase A (MAO-A) is an enzyme, encoded in the MAOA gene on the X chromosome, that is expressed on the outer surface of the mitochondrial membrane. Two isoforms of this enzyme are expressed on the ~~membrane~~, MAO-A and MAO-B, and both are responsible for the oxidation of various amine-containing neurotransmitters and dietary amines. More specifically, MAO-A oxidizes serotonin, epinephrine, and norepinephrine; while MAO-B oxidizes phenylethylamine and benzylamine. Both isoforms of monoamine oxidase oxidize dopamine, tyramine, and N,N-dimethyltryptamine. ''

Monoamine oxidase A (MAO-A) is an enzyme, encoded in the MAOA gene on the X chromosome, that is expressed on the outer surface of the mitochondrial membrane. Two isoforms of this enzyme are expressed in the same region, MAO-A and MAO-B, and both are responsible for the oxidation of various amine-containing neurotransmitters and dietary amines. More specifically, MAO-A oxidizes serotonin, epinephrine, and norepinephrine; while MAO-B oxidizes phenylethylamine and benzylamine. Both isoforms of monoamine oxidase oxidize dopamine, tyramine, and N,N-dimethyltryptamine.

Sandbox WWC2: Difference between revisions

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 ==Introduction==
-''Monoamine oxidase A (MAO-A) is an enzyme, encoded in the MAOA gene on the X chromosome, that is expressed on the outer surface of the mitochondrial membrane. Two isoforms of this enzyme are expressed on the membrane, MAO-A and MAO-B, and both are responsible for the oxidation of various amine-containing neurotransmitters and dietary amines. More specifically, MAO-A oxidizes serotonin, epinephrine, and norepinephrine; while MAO-B oxidizes phenylethylamine and benzylamine. Both isoforms of monoamine oxidase oxidize dopamine, tyramine, and N,N-dimethyltryptamine. ''
+Monoamine oxidase A (MAO-A) is an enzyme, encoded in the MAOA gene on the X chromosome, that is expressed on the outer surface of the mitochondrial membrane. Two isoforms of this enzyme are expressed in the same region, MAO-A and MAO-B, and both are responsible for the oxidation of various amine-containing neurotransmitters and dietary amines. More specifically, MAO-A oxidizes serotonin, epinephrine, and norepinephrine; while MAO-B oxidizes phenylethylamine and benzylamine. Both isoforms of monoamine oxidase oxidize dopamine, tyramine, and N,N-dimethyltryptamine.
 <Structure load='2Z5X' size='500' frame='top' align='right' caption='Crystal Structure of Human Monoamine Oxidase A with Harmine' scene='Insert optional scene name here' />