Major histocompatibility complex: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='3ox8' size=' | <StructureSection load='3ox8' size='450' side='right' caption='Human MHC class I antigen (cyan) with β 2-microglobulin (green) and peptide from Hepatitis virus (deeppink) [[3ox8]]' scene='45/457390/Cv/1'> | ||
== Function == | == Function == | ||
''' Major Histocompatibility Complex''' (MHC) are part of the cell immune system. MHC molecules display antigens on the host cell’s surface. T cell or natural killer receptors recognize the MHC:peptide and activate the immune response.<br /> | ''' Major Histocompatibility Complex''' (MHC) are part of the cell immune system. MHC molecules display antigens on the host cell’s surface. T cell or natural killer receptors recognize the MHC:peptide and activate the immune response.<br /> | ||
| Line 8: | Line 8: | ||
== Structural highlights == | == Structural highlights == | ||
<scene name='45/457390/Cv/3'>Human MHC class I antigen with β 2-microglobulin and peptide from Hepatitis virus</scene>. | |||
The peptide derived from Hepatitis virus binds MHC in a peptide-recognition groove and makes various interactions with side chains and with water molecules<ref>PMID:21538979</ref>. | The peptide derived from Hepatitis virus binds MHC in a peptide-recognition groove and makes various interactions with side chains and with water molecules<ref>PMID:21538979</ref>. | ||
</StructureSection> | </StructureSection> | ||
