TEM1 Class Antibiotic Resistance Proteins: Difference between revisions
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== Function == | == Function == | ||
There are two domains of this protein with the catalytic cleft in the shared region between the two domains. Mutations that occur in the catalytic region are able to slow down the catalysis that inactivates the antibiotics. | |||
== Disease == | == Disease == | ||
== Relevance | == Relevance = | ||
The frequency of mutations in bacteria make it an evolving resistance. The ability of TEM1 CLass Antibiotic Resistant protein to selectively mutate a single amino acid to inhibit the beta lactamase allows for a more adaptable resistance source. | |||
== Structural highlights == | == Structural highlights == | ||
