Lactoferrin: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
LTF is a bilobal protein with the <scene name='45/455488/Cv/2'>N-terminal half and the C-terminal half called N-lobe and C-lobe</scene>.  LTF binds with high affinity Fe+3 ion and an anion in both its N-lobe and its C-lobe<ref>PMID:8703903</ref>. The binding site is between the 2 domains of each lobe.  
LTF is a bilobal protein with the <scene name='45/455488/Cv/7'>N-terminal half and the C-terminal half called N-lobe and C-lobe</scene>.  LTF binds with high affinity Fe+3 ion and an anion in both its N-lobe and its C-lobe<ref>PMID:8703903</ref>. The binding site is between the 2 domains of each lobe.  


<scene name='45/455488/Cv/3'>N-lobe binding site</scene>.  
<scene name='45/455488/Cv/8'>N-lobe binding site</scene>.  


The <scene name='45/455488/Cv/4'>anion binds the Fe+3 in a 1,2 bidendate fashion</scene>.
The <scene name='45/455488/Cv/9'>anion binds the Fe+3 in a 1,2 bidendate fashion</scene>.


<scene name='45/455488/Cv/5'>C-lobe binding site</scene>.
<scene name='45/455488/Cv/10'>C-lobe binding site</scene>.


The <scene name='45/455488/Cv/6'>anion binds the Fe+3 in a 1,2 bidendate fashion</scene>.
The <scene name='45/455488/Cv/11'>anion binds the Fe+3 in a 1,2 bidendate fashion</scene>.


</StructureSection>
</StructureSection>

Revision as of 10:41, 4 July 2019

Human lactoferrin complex with oxalate and Fe+3 ion (PDB entry 1bka)

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3D Structures of lactoferrin

Updated on 04-July-2019

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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