Sandbox Reserved 1176: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 24: | Line 24: | ||
===Active-Like State=== | ===Active-Like State=== | ||
The six amino acid mutations for thermostabilization <ref name="SONT"/> were | The six amino acid mutations for thermostabilization <ref name="SONT"/> were Ala86Leu, Glu166Ala, Gly215Ala, Leu310Ala, Phe358Ala, and Val360Ala. This protein was found to have NTS affinity similar to that of wild tpye NTSR1, and was named <scene name='72/721547/Ntsr1-gw5/8'>NTSR1-GW5</scene>. Along with this, the Na+ ion binding pocket was collapsed in this protein. However, NTSR1-GW5 did not have G-protein activity <ref name="SONT"/>. | ||
===Active State=== | ===Active State=== | ||
