4zjc: Difference between revisions
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==Structures of the human OX1 orexin receptor bound to selective and dual antagonists== | ==Structures of the human OX1 orexin receptor bound to selective and dual antagonists== | ||
<StructureSection load='4zjc' size='340' side='right' caption='[[4zjc]], [[Resolution|resolution]] 2.83Å' scene=''> | <StructureSection load='4zjc' size='340' side='right'caption='[[4zjc]], [[Resolution|resolution]] 2.83Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zjc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZJC FirstGlance]. <br> | <table><tr><td colspan='2'>[[4zjc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZJC FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4OT:[5-(2-FLUOROPHENYL)-2-METHYL-1,3-THIAZOL-4-YL]{(2S)-2-[(5-PHENYL-1,3,4-OXADIAZOL-2-YL)METHYL]PYRROLIDIN-1-YL}METHANONE'>4OT</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4OT:[5-(2-FLUOROPHENYL)-2-METHYL-1,3-THIAZOL-4-YL]{(2S)-2-[(5-PHENYL-1,3,4-OXADIAZOL-2-YL)METHYL]PYRROLIDIN-1-YL}METHANONE'>4OT</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zj8|4zj8]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zj8|4zj8]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zjc OCA], [http://pdbe.org/4zjc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zjc RCSB], [http://www.ebi.ac.uk/pdbsum/4zjc PDBsum]</span></td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCRTR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zjc OCA], [http://pdbe.org/4zjc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zjc RCSB], [http://www.ebi.ac.uk/pdbsum/4zjc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zjc ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4zjc" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4zjc" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Orexin and Orexin receptor|Orexin and Orexin receptor]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Brautigam, C A]] | [[Category: Brautigam, C A]] | ||
[[Category: Clark, L]] | [[Category: Clark, L]] | ||
Revision as of 08:47, 26 June 2019
Structures of the human OX1 orexin receptor bound to selective and dual antagonists
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