5f3f: Difference between revisions

==Crystal structure of para-biphenyl-2-methyl-3'-methyl amide mannoside bound to FimH lectin domain==

<StructureSection load='5f3f' size='340' side='right' caption='[[5f3f]], [[Resolution|resolution]] 1.76&Aring;' scene=''>

<table><tr><td colspan='2'>[[5f3f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F3F FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5US:3-[4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(HYDROXYMETHYL)-3,4,5-TRIS(OXIDANYL)OXAN-2-YL]OXY-3-METHYL-PHENYL]-~{N}-METHYL-BENZAMIDE'>5US</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f3f OCA], [http://pdbe.org/5f3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f3f RCSB], [http://www.ebi.ac.uk/pdbsum/5f3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f3f ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.

[[Category: Hultgren, S J]]

[[Category: Sugar binding protein]]