5hod: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of LHX4 transcription factor complexed with DNA== | |||
<StructureSection load='5hod' size='340' side='right' caption='[[5hod]], [[Resolution|resolution]] 2.68Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5hod]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HOD FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hod OCA], [http://pdbe.org/5hod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hod RCSB], [http://www.ebi.ac.uk/pdbsum/5hod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hod ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Disease == | |||
[[http://www.uniprot.org/uniprot/LHX4_HUMAN LHX4_HUMAN]] Hypothyroidism due to deficient transcription factors involved in pituitary development or function;Pituitary stalk interruption syndrome;Short stature - pituitary and cerebellar defects - small sella turcica. The disease is caused by mutations affecting the gene represented in this entry. A chromosomal aberration involving LHX4 may be a cause of acute lymphoblastic leukemia. Translocation t(1;14)(q25;q32) with IGHG1.<ref>PMID:11567216</ref> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/LHX4_HUMAN LHX4_HUMAN]] May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Morgunova, E]] | |||
[[Category: Popov, A]] | [[Category: Popov, A]] | ||
[[Category: Taipale, J]] | |||
[[Category: Yin, Y]] | [[Category: Yin, Y]] | ||
[[Category: | [[Category: Complex with dna]] | ||
[[Category: | [[Category: Dimer]] | ||
[[Category: Transcription]] | |||
[[Category: Transcription factor]] | |||
Revision as of 18:04, 1 February 2017
Structure of LHX4 transcription factor complexed with DNA
| ||||||||||||
