5imu: Difference between revisions
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==A fragment of conserved hypothetical protein Rv3899c (residues 184-410) from Mycobacterium tuberculosis== | |||
<StructureSection load='5imu' size='340' side='right' caption='[[5imu]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5imu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IMU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IMU FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5imu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5imu OCA], [http://pdbe.org/5imu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5imu RCSB], [http://www.ebi.ac.uk/pdbsum/5imu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5imu ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Rv3899c is a hypothetical protein from Mycobacterium tuberculosis which is conserved across mycobacteria. It is predicted to be secreted and has been found in culture filtrates. It has been proposed as a potential vaccine candidate; however, its biological function is unknown. Here, the global structure of Rv3899c(184-410), a fragment of Rv3899c, is reported. The structure resembles the shell of a sea snail, and its N- and C-termini form two relatively independent compact domains: an alpha/beta/alpha sandwich folding domain and an alpha-helix bundle domain. There are no reported protein structures for any Rv3899c homologues; this structure provides the first structural glimpse of a new protein family consisting of Rv3899c and its homologues. | |||
Crystal structure of Rv3899c(184-410), a hypothetical protein from Mycobacterium tuberculosis.,Liu Y, Gao Y, Li D, Fleming J, Li H, Bi L Acta Crystallogr F Struct Biol Commun. 2016 Aug;72(Pt 8):642-5. doi:, 10.1107/S2053230X16010943. Epub 2016 Jul 27. PMID:27487929<ref>PMID:27487929</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
[[Category: Bi, L | <div class="pdbe-citations 5imu" style="background-color:#fffaf0;"></div> | ||
[[Category: Gao, Y | == References == | ||
[[Category: Li, D | <references/> | ||
[[Category: Liu, Y | __TOC__ | ||
</StructureSection> | |||
[[Category: Bi, L J]] | |||
[[Category: Gao, Y R]] | |||
[[Category: Li, D F]] | |||
[[Category: Liu, Y Y]] | |||
[[Category: Alpha helix bundule]] | |||
[[Category: Alpha/beta/alpha sandwich]] | |||
[[Category: Signaling protein]] | |||
Revision as of 16:48, 9 March 2017
A fragment of conserved hypothetical protein Rv3899c (residues 184-410) from Mycobacterium tuberculosis
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