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==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL0519==
==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL0519==
<StructureSection load='4rvi' size='340' side='right' caption='[[4rvi]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
<StructureSection load='4rvi' size='340' side='right'caption='[[4rvi]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4rvi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RVI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4rvi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RVI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G52:(3R,3AS,3BR,6AS,7AS)-OCTAHYDRODIFURO[2,3-B 3,2-D]FURAN-3-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}PROPYL]CARBAMATE'>G52</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G52:(3R,3AS,3BR,6AS,7AS)-OCTAHYDRODIFURO[2,3-B 3,2-D]FURAN-3-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}PROPYL]CARBAMATE'>G52</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4njs|4njs]], [[4njt|4njt]], [[4nju|4nju]], [[4njv|4njv]], [[4hla|4hla]], [[4rvj|4rvj]], [[4rvv|4rvv]], [[4rvx|4rvx]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4njs|4njs]], [[4njt|4njt]], [[4nju|4nju]], [[4njv|4njv]], [[4hla|4hla]], [[4rvj|4rvj]], [[4rvv|4rvv]], [[4rvx|4rvx]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvi OCA], [http://pdbe.org/4rvi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rvi RCSB], [http://www.ebi.ac.uk/pdbsum/4rvi PDBsum]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvi OCA], [http://pdbe.org/4rvi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rvi RCSB], [http://www.ebi.ac.uk/pdbsum/4rvi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvi ProSAT]</span></td></tr>
</table>
</table>
==See Also==
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Das, D]]
[[Category: Das, D]]
[[Category: Garimella, H]]
[[Category: Garimella, H]]

Revision as of 09:58, 1 May 2019

Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL0519

4rvi, resolution 1.99Å

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