5cxy: Difference between revisions
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==Structure of a Glycosyltransferase in Complex with Inhibitor== | |||
<StructureSection load='5cxy' size='340' side='right' caption='[[5cxy]], [[Resolution|resolution]] 2.15Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5cxy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CXY FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=55T:5-O-[(R)-[(S)-[3-(ACETYLAMINO)PHENYL](PHOSPHONO)METHOXY](HYDROXY)PHOSPHORYL]CYTIDINE'>55T</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bo6|5bo6]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cxy OCA], [http://pdbe.org/5cxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cxy RCSB], [http://www.ebi.ac.uk/pdbsum/5cxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cxy ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/SIA8C_HUMAN SIA8C_HUMAN]] May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.<ref>PMID:10766765</ref> <ref>PMID:9826427</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Strynadka, N C.J]] | |||
[[Category: Volkers, G]] | |||
[[Category: Inhibitor]] | |||
[[Category: Polysialyltransferase]] | |||
[[Category: Sialyltransferase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 21:01, 10 September 2016
Structure of a Glycosyltransferase in Complex with Inhibitor
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