5ild: Difference between revisions
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==Tobacco 5-epi-aristolochene synthase with MES buffer molecule and Mg2+ ions== | |||
<StructureSection load='5ild' size='340' side='right' caption='[[5ild]], [[Resolution|resolution]] 2.12Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ild]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ILD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ILD FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ik0|5ik0]], [[5ik6|5ik6]], [[5ik9|5ik9]], [[5ika|5ika]], [[5ikh|5ikh]], [[5il3|5il3]], [[5il8|5il8]], [[5ilh|5ilh]], [[5ili|5ili]], [[5ilj|5ilj]], [[5ilk|5ilk]], [[5ily|5ily]], [[5ilz|5ilz]], [[5im1|5im1]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-epiaristolochene_synthase 5-epiaristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.61 4.2.3.61] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ild FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ild OCA], [http://pdbe.org/5ild PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ild RCSB], [http://www.ebi.ac.uk/pdbsum/5ild PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ild ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: 5-epiaristolochene synthase]] | |||
[[Category: Bowman, M]] | |||
[[Category: Koo, H J]] | |||
[[Category: Louie, G V]] | |||
[[Category: Noel, J P]] | |||
[[Category: Xu, Y]] | |||
[[Category: Lyase]] | |||
[[Category: Me]] | |||
[[Category: Tea]] | |||
[[Category: Terpene synthase]] | |||