5ith: Difference between revisions
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==TIA-1 RRM2 recognition of target oligonucleotide== | |||
<StructureSection load='5ith' size='340' side='right' caption='[[5ith]], [[Resolution|resolution]] 2.31Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ITH FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [http://pdbe.org/5ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [http://www.ebi.ac.uk/pdbsum/5ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Waris, S]] | |||
[[Category: Wilce, J A]] | |||
[[Category: Wilce, M C]] | |||
[[Category: Aromatic base stacking interaction]] | |||
[[Category: Dna binding protein-dna complex]] | |||
[[Category: Poly u binding preference]] | |||
[[Category: Rna binding protein-dna complex]] | |||
[[Category: Rna/dna binding domain]] | |||
[[Category: Rrm]] | |||
Revision as of 01:34, 11 March 2017
TIA-1 RRM2 recognition of target oligonucleotide
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