5ix2: Difference between revisions
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==Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and unmodified H3 peptide== | |||
<StructureSection load='5ix2' size='340' side='right' caption='[[5ix2]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ix2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IX2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ix1|5ix1]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ix2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ix2 OCA], [http://pdbe.org/5ix2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ix2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ix2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ix2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MORC3_MOUSE MORC3_MOUSE]] Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (By similarity). Sumoylated MORC3-NBs can also associate with PML-NBs (By similarity). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (By similarity).[UniProtKB:Q14149]<ref>PMID:17332504</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Du, J]] | |||
[[Category: Li, S]] | |||
[[Category: Patel, D J]] | |||
[[Category: Atpase]] | |||
[[Category: Cw domain]] | |||
[[Category: H3]] | |||
[[Category: Morc3]] | |||
[[Category: Transcription]] | |||
Revision as of 00:04, 10 September 2016
Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and unmodified H3 peptide
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