5j5j: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~5j5j is ON HOLD until Paper Publication~~

==Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5j5j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J5J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J5J FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j5j OCA], [http://pdbe.org/5j5j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j5j RCSB], [http://www.ebi.ac.uk/pdbsum/5j5j PDBsum]</span></td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/DSC2_HUMAN DSC2_HUMAN]] Familial isolated arrhythmogenic ventricular dysplasia, right dominant form;Familial isolated arrhythmogenic ventricular dysplasia, biventricular form;Familial isolated arrhythmogenic ventricular dysplasia, left dominant form. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/DSC2_HUMAN DSC2_HUMAN]] Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

__TOC__

</StructureSection>

[[Category: Brasch, J]]

[[Category: Harrison, O J]]

[[Category: Shapiro, L]]

[[Category: Cell adhesion]]

[[Category: Cell surface]]

[[Category: Desmosome]]

[[Category: Extracellular cadherin domain]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5j5j is ON HOLD  until Paper Publication
+==Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5==
+<StructureSection load='5j5j' size='340' side='right' caption='[[5j5j]], [[Resolution|resolution]] 3.29&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5j5j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J5J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J5J FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j5j OCA], [http://pdbe.org/5j5j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j5j RCSB], [http://www.ebi.ac.uk/pdbsum/5j5j PDBsum]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/DSC2_HUMAN DSC2_HUMAN]] Familial isolated arrhythmogenic ventricular dysplasia, right dominant form;Familial isolated arrhythmogenic ventricular dysplasia, biventricular form;Familial isolated arrhythmogenic ventricular dysplasia, left dominant form. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/DSC2_HUMAN DSC2_HUMAN]] Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
+__TOC__
+</StructureSection>
+[[Category: Brasch, J]]
+[[Category: Harrison, O J]]
+[[Category: Shapiro, L]]
+[[Category: Cell adhesion]]
+[[Category: Cell surface]]
+[[Category: Desmosome]]
+[[Category: Extracellular cadherin domain]]