5jj2: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5jj2 is ~~ON HOLD until Paper Publication~~

==Crystal structure of the central domain of human AKAP18 gamma/delta in complex with malonate==

~~Authors~~: ~~Bjerregaard~~-~~Andersen~~, K., ~~Ostensen~~, E., ~~Scott~~, J.D., ~~Tasken~~, K., Morth, J.P.

== Structural highlights ==

<table><tr><td colspan='2'>[[5jj2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JJ2 FirstGlance]. <br>

~~Description~~: ~~Crystal structure of the central domain of human AKAP18 gamma/delta in complex with malonate~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jj2 OCA], [http://pdbe.org/5jj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jj2 RCSB], [http://www.ebi.ac.uk/pdbsum/5jj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jj2 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/AKA7G_HUMAN AKA7G_HUMAN]] Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.<ref>PMID:10613906</ref> <ref>PMID:17244820</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Bjerregaard-Andersen, K]]

[[Category: Morth, J P]]

[[Category: Ostensen, E]]

[[Category: Scott, J D]]

[[Category: Tasken, K]]

[[Category: ~~Scott, J.D~~]]

[[Category: A-kinase anchoring]]

[[Category: ~~Ostensen, E~~]]

[[Category: Akap]]

[[Category: ~~Morth, J.P~~]]

[[Category: Central domain]]

[[Category: ~~Bjerregaard-Andersen, K~~]]

[[Category: Complex]]

[[Category: Hydrolase]]

[[Category: Malonate]]

[[Category: Phospoesterase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5jj2 is ON HOLD  until Paper Publication
+==Crystal structure of the central domain of human AKAP18 gamma/delta in complex with malonate==
+<StructureSection load='5jj2' size='340' side='right' caption='[[5jj2]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
-Authors: Bjerregaard-Andersen, K., Ostensen, E., Scott, J.D., Tasken, K., Morth, J.P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5jj2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JJ2 FirstGlance]. <br>
-Description: Crystal structure of the central domain of human AKAP18 gamma/delta in complex with malonate
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jj2 OCA], [http://pdbe.org/5jj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jj2 RCSB], [http://www.ebi.ac.uk/pdbsum/5jj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jj2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/AKA7G_HUMAN AKA7G_HUMAN]] Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.<ref>PMID:10613906</ref> <ref>PMID:17244820</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Bjerregaard-Andersen, K]]
+[[Category: Morth, J P]]
+[[Category: Ostensen, E]]
+[[Category: Scott, J D]]
 [[Category: Tasken, K]]
-[[Category: Scott, J.D]]
+[[Category: A-kinase anchoring]]
-[[Category: Ostensen, E]]
+[[Category: Akap]]
-[[Category: Morth, J.P]]
+[[Category: Central domain]]
-[[Category: Bjerregaard-Andersen, K]]
+[[Category: Complex]]
+[[Category: Hydrolase]]
+[[Category: Malonate]]
+[[Category: Phospoesterase]]