5jka: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5jka is ~~ON HOLD until Paper Publication~~

==Crystal structure of human JUNO (crystal form 1)==

~~Authors~~: ~~Ohto~~, U., ~~Ishida~~, H., ~~Shimizu~~, T.

== Structural highlights ==

<table><tr><td colspan='2'>[[5jka]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JKA OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JKA FirstGlance].

~~Description: Crystal structure of human JUNO (crystal form 1)~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

[~~[Category~~: ~~Shimizu, T]~~]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jka OCA], [http://pdbe.org/5jka PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jka RCSB], [http://www.ebi.ac.uk/pdbsum/5jka PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/JUNO_HUMAN JUNO_HUMAN]] Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.[UniProtKB:Q9EQF4]

__TOC__

</StructureSection>

[[Category: Ishida, H]]

[[Category: Ohto, U]]

[[Category: Shimizu, T]]

[[Category: Cell adhesion]]

[[Category: Fertilization]]

[[Category: Izumo1]]

[[Category: Juno]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5jka is ON HOLD  until Paper Publication
+==Crystal structure of human JUNO (crystal form 1)==
+<StructureSection load='5jka' size='340' side='right' caption='[[5jka]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors: Ohto, U., Ishida, H., Shimizu, T.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5jka]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JKA FirstGlance]. <br>
-Description: Crystal structure of human JUNO (crystal form 1)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jke|5jke]], [[5jkd|5jkd]], [[5jkc|5jkc]], [[5jkb|5jkb]], [[5jk9|5jk9]]</td></tr>
-[[Category: Shimizu, T]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jka OCA], [http://pdbe.org/5jka PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jka RCSB], [http://www.ebi.ac.uk/pdbsum/5jka PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/JUNO_HUMAN JUNO_HUMAN]] Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.[UniProtKB:Q9EQF4]
+__TOC__
+</StructureSection>
 [[Category: Ishida, H]]
 [[Category: Ohto, U]]
+[[Category: Shimizu, T]]
+[[Category: Cell adhesion]]
+[[Category: Fertilization]]
+[[Category: Izumo1]]
+[[Category: Juno]]