Nucleoplasmin: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 1: Line 1:
{{STRUCTURE_1k5j|  PDB=1k5j | SIZE=400| SCENE= |right|CAPTION=Nucleoplasmin core pentamer, [[1k5j]] }}
 
<StructureSection load='1k5j' size='350' side='right' caption='Nucleoplasmin core pentamer (PDB entry [[1k5j]])' scene=''>
== Function ==
== Function ==
'''Nucleoplasmin''' (Npl) is a molecular chaperone.  Npl functions in the proper assembly of nucleosomes and chromatin structures<ref>PMID:15284896</ref>.
'''Nucleoplasmin''' (Npl) is a molecular chaperone.  Npl functions in the proper assembly of nucleosomes and chromatin structures<ref>PMID:15284896</ref>.
Line 5: Line 6:
== Relevance ==
== Relevance ==
Apoptotic chromatin condensation, one of the hallmarks of apoptosis, is regulated by Npl.
Apoptotic chromatin condensation, one of the hallmarks of apoptosis, is regulated by Npl.
</StructureSection>


==3D structures of nucleoplasmin==
==3D structures of nucleoplasmin==

Revision as of 10:18, 27 August 2017

Nucleoplasmin core pentamer (PDB entry 1k5j)

Drag the structure with the mouse to rotate

3D structures of nucleoplasmin

1k5j – XlNpl core – Xenopus laevis

2vtx - XlNpl core (mutant)

3t30 – Npl oligomerisation domain - human

1ee5, 1ejy –XlNpl nuclear localization peptide + karyopherin-a

References

Proteopedia Page Contributors and Editors (what is this?)

Tomer Gelman, Michal Harel, Jaime Prilusky