5jt0: Difference between revisions
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==Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis in complex with Mn2+, uridine-diphosphate (UDP) and glucosyl-3-phosphoglycerate (GPG) - GpgS*GPG*UDP*Mn2+== | |||
<StructureSection load='5jt0' size='340' side='right' caption='[[5jt0]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5jt0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JT0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JT0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene>, <scene name='pdbligand=XDX:(2R)-2-(ALPHA-D-GLUCOPYRANOSYLOXY)-3-(PHOSPHONOOXY)PROPANOIC+ACID'>XDX</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jsx|5jsx]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosyl-3-phosphoglycerate_synthase Glucosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.266 2.4.1.266] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jt0 OCA], [http://pdbe.org/5jt0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jt0 RCSB], [http://www.ebi.ac.uk/pdbsum/5jt0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jt0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GPGS_MYCTU GPGS_MYCTU]] Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of NDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG).<ref>PMID:22637481</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Glucosyl-3-phosphoglycerate synthase]] | |||
[[Category: Albesa-Jove, D]] | |||
[[Category: Arrasate, P]] | |||
[[Category: Carreras-Gonzalez, A]] | |||
[[Category: Comino, N]] | |||
[[Category: Guerin, M E]] | |||
[[Category: Rodrigo-Unzueta, A]] | |||
[[Category: Sancho-Vaello, E]] | |||
[[Category: Urresti, S]] | |||
[[Category: Transferase]] | |||
Revision as of 13:43, 24 May 2017
Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis in complex with Mn2+, uridine-diphosphate (UDP) and glucosyl-3-phosphoglycerate (GPG) - GpgS*GPG*UDP*Mn2+
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