5jyj: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry 5jyj~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of mouse JUNO==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5jyj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JYJ FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyj OCA], [http://pdbe.org/5jyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jyj RCSB], [http://www.ebi.ac.uk/pdbsum/5jyj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyj ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/JUNO_MOUSE JUNO_MOUSE]] Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.<ref>PMID:24739963</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Ishitani, R]]

[[Category: Kato, K]]

[[Category: Morita, J]]

[[Category: Nishimasu, H]]

[[Category: Nureki, O]]

[[Category: Cell adhesion]]

[[Category: Fertilization]]

[[Category: Folate receptor]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5jyj is ON HOLD  until Paper Publication
+==Crystal structure of mouse JUNO==
+<StructureSection load='5jyj' size='340' side='right' caption='[[5jyj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5jyj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JYJ FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyj OCA], [http://pdbe.org/5jyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jyj RCSB], [http://www.ebi.ac.uk/pdbsum/5jyj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyj ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/JUNO_MOUSE JUNO_MOUSE]] Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.<ref>PMID:24739963</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Ishitani, R]]
+[[Category: Kato, K]]
+[[Category: Morita, J]]
+[[Category: Nishimasu, H]]
+[[Category: Nureki, O]]
+[[Category: Cell adhesion]]
+[[Category: Fertilization]]
+[[Category: Folate receptor]]