5l87: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5l87 is ON HOLD~~

==Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.==

~~Authors: Dawidowski, M., Emmanouilidis, L., Sattler, M., Popowicz, G.M.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5l87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L87 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L87 FirstGlance].

~~Description:~~ Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=6RD:5-(1~{H}-INDOL-3-YLMETHYL)-1-METHYL-~{N}-(NAPHTHALEN-1-YLMETHYL)-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE'>6RD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[2w84|2w84]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l87 OCA], [http://pdbe.org/5l87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l87 RCSB], [http://www.ebi.ac.uk/pdbsum/5l87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l87 ProSAT]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Dawidowski, M]]

[[Category: Emmanouilidis, L]]

[[Category: Popowicz, G M]]

[[Category: Sattler, M]]

[[Category: ~~Popowicz, G.M~~]]

[[Category: Glycosome]]

[[Category: Inhibitor]]

[[Category: Membrane protein]]

[[Category: Protein-protein interaction inhibitor]]

[[Category: Structure-based drug discovery]]

[[Category: Trypanosomiasis]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5l87 is ON HOLD
+==Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.==
+<StructureSection load='5l87' size='340' side='right' caption='[[5l87]], [[Resolution|resolution]] 0.87&Aring;' scene=''>
-Authors: Dawidowski, M., Emmanouilidis, L., Sattler, M., Popowicz, G.M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5l87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L87 FirstGlance]. <br>
-Description: Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6RD:5-(1~{H}-INDOL-3-YLMETHYL)-1-METHYL-~{N}-(NAPHTHALEN-1-YLMETHYL)-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE'>6RD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w84|2w84]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l87 OCA], [http://pdbe.org/5l87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l87 RCSB], [http://www.ebi.ac.uk/pdbsum/5l87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l87 ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
 [[Category: Dawidowski, M]]
 [[Category: Emmanouilidis, L]]
+[[Category: Popowicz, G M]]
 [[Category: Sattler, M]]
-[[Category: Popowicz, G.M]]
+[[Category: Glycosome]]
+[[Category: Inhibitor]]
+[[Category: Membrane protein]]
+[[Category: Protein-protein interaction inhibitor]]
+[[Category: Structure-based drug discovery]]
+[[Category: Trypanosomiasis]]