5hq5: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5hq5 is ~~ON HOLD until Paper Publication~~

==Crystal structure of fragment bound with Brd4==

~~Authors~~: ~~Chen~~, T.T., Xu, Y.C.

== Structural highlights ==

<table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HQ5 FirstGlance].

~~Description~~: ~~Crystal structure~~ of ~~fragment bound~~ with ~~Brd4~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=64Q:7-METHYL-N-(O-TOLYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-5-AMINE'>64Q</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5hq6|5hq6]], [[5hq7|5hq7]]</td></tr>

[[Category: Xu, Y.C]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [http://pdbe.org/5hq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [http://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</td></tr>

[[Category: ~~Chen, T.T~~]]

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>

== Function ==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

== References ==

__TOC__

</StructureSection>

[[Category: Chen, T T]]

[[Category: Xu, Y C]]

[[Category: Brd4]]

[[Category: Transcription]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5hq5 is ON HOLD  until Paper Publication
+==Crystal structure of fragment bound with Brd4==
+<StructureSection load='5hq5' size='340' side='right' caption='[[5hq5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-Authors: Chen, T.T., Xu, Y.C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HQ5 FirstGlance]. <br>
-Description: Crystal structure of fragment bound with Brd4
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=64Q:7-METHYL-N-(O-TOLYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-5-AMINE'>64Q</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hq6|5hq6]], [[5hq7|5hq7]]</td></tr>
-[[Category: Xu, Y.C]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [http://pdbe.org/5hq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [http://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</span></td></tr>
-[[Category: Chen, T.T]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Chen, T T]]
+[[Category: Xu, Y C]]
+[[Category: Brd4]]
+[[Category: Transcription]]