5k8y: Difference between revisions
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==Structure of the Mus musclus Langerin carbohydrate recognition domain== | |||
<StructureSection load='5k8y' size='340' side='right' caption='[[5k8y]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5k8y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K8Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K8Y FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k8y OCA], [http://pdbe.org/5k8y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k8y RCSB], [http://www.ebi.ac.uk/pdbsum/5k8y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k8y ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CLC4K_MOUSE CLC4K_MOUSE]] Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.<ref>PMID:11777972</ref> <ref>PMID:18322168</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Aretz, J]] | |||
[[Category: Loll, B]] | |||
[[Category: Rademacher, C]] | |||
[[Category: Wahl, M C]] | |||
[[Category: C-type lectin]] | |||
[[Category: Calcium binding]] | |||
[[Category: Carbohydrate binding protein]] | |||
[[Category: Crd domain]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Immune system]] | |||
[[Category: Lectin]] | |||
Revision as of 02:15, 11 December 2016
Structure of the Mus musclus Langerin carbohydrate recognition domain
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