Pre-mRNA-splicing factor: Difference between revisions
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*'''Prp18''' and '''Bud31''' are essential for the catalytic step in pre-mRNA splicing process.<br /> | *'''Prp18''' and '''Bud31''' are essential for the catalytic step in pre-mRNA splicing process.<br /> | ||
*'''snRNA-associated-splicing factor 24''' binds preferentially to the U4/U6 hybrid snRNAs. For details see [[Prp24]]<br /> | *'''snRNA-associated-splicing factor 24''' binds preferentially to the U4/U6 hybrid snRNAs. For details see [[Prp24]]<br /> | ||
*[[Prp19]]<br /> | *For '''Prp19''' see [[Prp19]]<br /> | ||
*[[Prp40]].<br /> | *'''Prp31''' functions in forming the U4/U5-U6 tri-snRNP.<br /> | ||
*For '''Prp40''' see [[Prp40]].<br /> | |||
*'''Prpcwc2''' is a yeast splicing factor which plays a role in the generation of a functional splicing center '''Prp RBM22''' is the human homolog of Prpcwc2.<br /> | *'''Prpcwc2''' is a yeast splicing factor which plays a role in the generation of a functional splicing center '''Prp RBM22''' is the human homolog of Prpcwc2.<br /> | ||
*'''Prpcwc26''' or '''Bud13''' belongs to the pre-mRNA retention and splicing complex RES.<br /> | *'''Prpcwc26''' or '''Bud13''' belongs to the pre-mRNA retention and splicing complex RES.<br /> | ||
== Disease == | |||
Mutations in Prp8 and Prp31 cause retinitis pigmentosa<ref>PMID:11468273</ref>. | |||
== 3D Structures of pre-mRNA splicing factors == | == 3D Structures of pre-mRNA splicing factors == | ||
