5d1x: Difference between revisions
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==IsdB NEAT2 bound by D4-30== | |||
<StructureSection load='5d1x' size='340' side='right' caption='[[5d1x]], [[Resolution|resolution]] 3.21Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5d1x]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D1X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D1X FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d1q|5d1q]], [[5d1z|5d1z]]</td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d1x OCA], [http://pdbe.org/5d1x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d1x RCSB], [http://www.ebi.ac.uk/pdbsum/5d1x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d1x ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ISDB_STAA3 ISDB_STAA3]] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Deng, X]] | [[Category: Deng, X]] | ||
[[Category: Germline encoded]] | |||
[[Category: Immune system]] | |||
[[Category: Isdb]] | |||
[[Category: Neat2]] | |||
