5cjp: Difference between revisions
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The | ==The Structural Basis for Cdc42-Induced Dimerization of IQGAPs== | ||
<StructureSection load='5cjp' size='340' side='right' caption='[[5cjp]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5cjp]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CJP FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjp OCA], [http://pdbe.org/5cjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cjp RCSB], [http://www.ebi.ac.uk/pdbsum/5cjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjp ProSAT]</span></td></tr> | ||
[[Category: Boyapati, V | </table> | ||
[[Category: | == Function == | ||
[[Category: Worthylake, D | [[http://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN]] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Boyapati, V K]] | |||
[[Category: Jr, L LeCour]] | |||
[[Category: Worthylake, D K]] | |||
[[Category: Iqgap2 gap related domain x-ray gtpase interactions complex cdc42]] | |||
[[Category: Protein binding]] | |||
Revision as of 16:19, 10 August 2016
The Structural Basis for Cdc42-Induced Dimerization of IQGAPs
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